Hipertensão arterial sistêmica autorrelatada em pacientes atendidos no curso de Odontologia da Unigranrio e sua relação com parâmetros periodontais e CPOD / Self-reported systemic arterial hypertension in patients treated at Unigranrio's Dentistry course and its relationship with periodontal parameters and DMFT

Objetivo: Avaliar a frequência de hipertensão arterial sistêmica e sua associação com parâmetros periodontais e do índice de dentes cariados, perdidos, obturados (CPOD) em indivíduos atendidos na clínica do Curso de Odontologia da Unigranrio. Materiais e métodos: Noventa e cinco indivíduos de ambos os sexos foram incluídos no estudo entre março e maio de 2021. Os participantes responderam a questionários anamnésicos, tiveram sua pressão arterial sistêmica aferida e foram examinados para obtenção do índice CPOD e de parâmetros periodontais. Resultados: A frequência de hipertensão arterial sistêmica na população estudada foi 23,15%. Em pacientes com periodontite, essa prevalência foi 27%, e, em pacientes com gengivite, 19%. Pacientes com periodontite tiveram médias superiores de pressão arterial sistólica (PAS) e diastólica (PAD) comparado ao grupo com gengivite (p<0,0001). Foram identificadas correlações significativas positivas entre PAS e bolsas periodontais moderadas (rho=0,356) e profundas (rho=0,342), perda de inserção avançada (rho=0,538), CPOD (rho=0,365) e quantidade de dentes ausentes (rho=0,477), p < 0,001. A PAD apresentou correlações significativas (p < 0,001) positivas com bolsas periodontais moderadas (rho=0,331) e profundas (rho=0,283), perda de inserção avançada (rho=0,465), CPOD (rho=0,361) e dentes ausentes (rho=0,348). Conclusões: A frequência de hipertensão arterial sistêmica autorrelatada é relativamente alta na população estudada e, em especialmente, dentre as pessoas com periodontite. Pressão arterial sistólica e diastólica são correlacionadas positivamente com parâmetros periodontais indicadores de severidade de doença, assim como piores escores do CPOD.

Aim: The study evaluated the prevalence of systemic arterial hypertension and its association with periodontal parameters and decayed-missing-filled teeth (DMFT) index in individuals treated in a Dental School clinic. Material and methods: Ninety-five individuals of both genders were included in the study in the period between March and May 2021. All participants answered anamnestic questionaries, had their systemic blood pressure measured, and were examined to obtain the DMFT and periodontal parameters. Results: The prevalence of systemic arterial hypertension in the study population was 23.15%. In periodontitis individuals, that prevalence was 27%, and, in gingivitis patients, 19%. Patients with periodontitis have higher mean systolic (SBP) and diastolic (DBP) blood pressure compared with gingivitis individuals (p<0.0001). Significant positive correlations were found between SBP and moderate (rho=0.356) and deep (rho=0.342) periodontal pockets, severe attachment loss (rho=0.538), DMFT (rho=0.365), and amount of missing teeth (rho=0.477), p ? 0.001. The DBP showed significant (p?0.001) positive correlations with moderate (rho=0.331) and (rho=0.283) deep periodontal pockets, severe attachment loss (rho=0.465), DMFT (rho=0.361), and missing teeth (rho=0.348). Conclusions: The prevalence of systemic arterial hypertension is relatively high in the study population and, in particular, among individuals with periodontitis. Systolic and diastolic blood pressure are positively correlated with periodontal parameters that indicate the severity of disease, as well as with worse DMFT scores.

Multiple Brain Abscesses Secondary to Odontogenic Infection: A Clinical Case Report

Introduction Cerebral abscess is a suppurative infection of the cerebral parenchyma, which may occur due to contiguity, hematogenous dissemination of distant foci, secondary to open traumatic brain injuries, or be idiopathic. Clinical Case A 63-year-old male patient sought assistance due to a severe headache in the frontal region associated with chills and lack of appetite that started four days before. Clinical examination of the patient showed no significant changes. Imaging and laboratory tests on admission showed only nonspecific changes, such as leukocytes 18,540, platelets 517,000, and c-reactive protein 2,0. In such case,magnetic resonance imaging (MRI) of the skull was performed with contrast, showing the presence of expansive lesions compatible with multiple brain abscesses in the right parietooccipital region. Discussion After excluding the main focus of hematogenous dissemination and in view of the identification of the agent Streptococcus intermedius by means of secretion culture collected through a surgical method, the hypothesis of abscess due to contiguous dental pyogenic foci was pointed out. Conclusion Dental evaluation showed multiple foci of infection with periodontitis and dental abscess, which were treated along with the use of antibiotics directed to the etiologic agent.

Impact of periodontal disease on late morbimortality (10 years) of pacientes with acute coronary syndrome / Impacto da doença periodontal na morbimortalidade tardia (10 anos) de pacientes com síndrome coronariana aguda

Background: It is known that predisposing factors for periodontal disease (PD) and cardiovascular diseases are similar, just as dissemination of oral flora pathogens can induce the development of cardiovascular diseases, which play a direct role on the morbimortality of patients. Objective: To assess the impact of periodontal disease in the presence of acute coronary syndrome on late morbimortality after long-term follow-up of patients (10 years). Methods: The historical prospective study of continuous assessment was based on the evaluation of 345 medical records of patients hospitalized for acute coronary syndrome, divided into 3 groups: edentulous, with periodontal disease and without periodontal disease. The patients studied were in the ICU, in 2006, with a clinical picture of acute coronary syndrome submitted to invasive stratification with coronary angiography on the basis of clinical indication and were reassessed over the next 10 years. The qualitative variables were compared using the Chi-square test. Long-term mortality was assessed using the Kaplan-Meier curves, quantified with the hazard ratio (HR) and a confidence interval of 95% and compared through Cox regression. P values of less than or equal to 0.05 were regarded as statistically significant. Results: Of the 345 patients, 233 had at least one coronary obstruction greater than or equal to 50%, being the main group for comparison according to the different status of periodontal disease (without periodontal disease, with periodontal disease and edentulous). In his cardiovascular condition, we found a difference in mortality among edentulous patients compared to those free of periodontal disease, with a p = 0.004 and a hazard ratio of 10.496 (95% CI: 4.988-22.089). A is ignificant difference was also noted between edentulous patients and patients with periodontal disease, with a p = 0.0017 and a hazard ratio of 2.512 (95% CI: 1.491-4.234). Conclusion: A significant increase in mortality was found according with the progression of periodontal disease, which justifies its classification as an important risk factor for the development of cardiovascular diseases, as well as the need for prevention and treatment of oral diseases

Inflammatory markers in the saliva of cerebral palsy individuals with gingivitis after periodontal treatment

Abstract The aim of this study was to evaluate the effect of periodontal treatment on the salivary cytokine levels and clinical parameters of individuals with cerebral palsy (CP) with gingivitis. A non-randomized, clinical trial was conducted in individuals diagnosed with spastic CP. Thirty-eight individuals were enrolled in the study and were categorized according to gingival index scores between 0-1 or 2-3, assigned to groups G2 or G1, respectively. Periodontal treatment comprised oral hygiene instructions, conventional mechanical treatment and 0.12% chlorhexidine applied as an adjunct. Clinical parameters and saliva samples were collected at baseline and at the 15-day follow-up visit. Bleeding on probing and periodontal screening and recording were determined. Non-stimulated saliva samples were obtained, and the salivary flow rate, the osmolality and the levels of cytokines IL-1β, IL-6, IL-8, IL-10, TNF-α and IL-12p70 were evaluated by a cytometric bead array. The Wilcoxon test, the Mann-Whitney test, Spearman correlation analysis, Poisson regression analysis and an adjusted analysis were performed (α = 0.05). The groups differed significantly in periodontal clinical parameters at baseline and at follow-up. Salivary flow rate and osmolality were similar in both groups at both timepoints. However, TNF-α and IL-1β levels were higher in G1 than in G2 at baseline. Mechanical treatment resulted in improved clinical parameters for both groups. Furthermore, mechanical treatment resulted in a significant reduction in salivary IL-1β and IL-8 levels for both groups after treatment. Periodontal treatment performed in individuals with CP and gingivitis reduces the levels of TNF-α, IL-1β, IL-6 and IL-8.

Relationship between periodontal disease and cardiovascular risk factors among young and middle-aged Brazilians. Cross-sectional study / Relação entre doença periodontal e fatores de risco cardiovascular em brasileiros jovens e de meia-idade. Estudo transversal

ABSTRACT CONTEXT AND OBJECTIVE: It has been suggested in the literature that periodontal disease (PD) is associated with cardiovascular risk. The objective of this study was to appraise the relationship between periodontal disease (gingivitis and periodontitis) and traditional cardiovascular risk factors (obesity, hypertension, dyslipidemia, diabetes and metabolic syndrome) among young and middle-aged adults attended at a health promotion and check-up center in the city of São Paulo, Brazil. DESIGN AND SETTING: Cross-sectional study at the Health Promotion and Check-up Center of Hospital Sírio-Libanês, São Paulo, Brazil. METHODS: We consecutively evaluated 539 subjects without prior cardiovascular disease who were seen within a health promotion program that included cardiovascular and dental evaluation between February and November 2012. Odds ratios (OR) with respective 95% confidence intervals (95% CI) for the association between PD and cardiovascular risk factors were ascertained through multinomial logistic regression. RESULTS: In this sample of mean age 45 years (standard deviation, SD ± 8.8), which was 82% male, we found PD in 63.2% (gingivitis 50.6% and periodontitis 12.6%). Individuals with PD were older, more obese (without PD 15.2%; versus gingivitis 22.1% and periodontitis 32.4%) and more diabetic (without PD 5.1%; versus gingivitis 4.8% and periodontitis 13.2%), compared with those without PD. Among all cardiovascular risk factors evaluated, obesity was associated with periodontitis (multivariate OR, 2.36; 95% CI, 1.23-4.52). However, after additional adjustment for oral hygiene, this finding was no longer significant (multivariate OR, 1.63; 95% CI, 0.79-3.37). CONCLUSIONS: We did not find any significant associations between cardiovascular risk factors and periodontal disease in this sample.

RESUMO CONTEXTO E OBJETIVO: A literatura sugere que doença periodontal (DP) está associada ao risco cardiovascular. O objetivo deste estudo foi avaliar a relação entre doença periodontal (gengivite e periodontite) e fatores de risco cardiovasculares tradicionais (obesidade, hipertensão, dislipidemia, diabetes e síndrome metabólica) em adultos jovens e de meia-idade atendidos em um centro de promoção da saúde e check-up na cidade de São Paulo, Brasil. TIPO DE ESTUDO E LOCAL: Estudo transversal no Centro de Promoção de Saúde e check-up do Hospital Sírio-Libanês, São Paulo, Brasil. MÉTODOS: Avaliamos consecutivamente 539 indivíduos sem doença cardiovascular diagnosticada, observados em um programa de promoção da saúde que incluiu avaliação cardiovascular e odontológica de fevereiro a novembro de 2012. Razões de chances (RC) com respectivos intervalos de confiança de 95% (IC 95%) para a associação entre DP e fatores de risco cardiovascular foram calculadas por regressão logística multinomial. RESULTADOS: Nesta amostra de pessoas com idade média de 45 anos (desvio padrão, DP ± 8,8), 82% de homens, encontramos 63,2% de casos de DP (50,6% de gengivite e periodontite 12,6%). Indivíduos com DP eram mais velhos, mais obesos (sem DP 15,2%; versus gengivite 22,1% e periodontite 32,4%) e mais diabéticos (sem DP 5,1%; versus gengivite 4,8% e periodontite 13,2%) comparados com aqueles sem DP. De todos os fatores de risco cardiovascular avaliados, a obesidade foi associada à periodontite (RC multivariada, 2,36; IC 95%, 1,23-4,52). No entanto, após ajuste adicional para higiene bucal, esse achado não foi mais significativo (RC multivariada, 1,63; IC 95%, 0,79-3,37). CONCLUSÕES: Não encontramos associações significativas entre fatores de risco cardiovascular e doença periodontal nesta amostra.

Enfermedad periodontal en adolescentes / Periodontal disease in teenagers

Introducción: durante mucho tiempo se creyó que la enfermedad periodontal era una afección de la adultez, sin embargo la falta de motivación en la práctica de la higiene oral en la etapa de la adolescencia condiciona su aparición. Objetivo: identificar el estado periodontal en adolescentes de la escuela Secundaria Básica Urbana ¨Raúl Pujols¨, en la ciudad de Santiago de Cuba, en el periodo de septiembre 2014 hasta marzo 2015. Materiales y Métodos: se realizó un estudio observacional, descriptivo transversal. El universo estuvo constituido por los 75 adolescentes, entre 11 a 14 años de edad de ambos sexos. Se utilizó el índice periodontal de Russell revisado por la Organización Mundial de la Salud y el índice de Love. Se confeccionó una planilla de recolección de datos para los resultados del examen físico y como medidas de resumen se usó el porcentaje. Resultados: prevaleció la gingivitis leve en el 66,7 % de los adolescentes, relacionado a la existencia de una higiene bucal deficiente. Predominó el sexo femenino y los factores de riesgo más encontrados fueron el apiñamiento dentario y los hábitos deletéreos. Conclusiones: la mayoría de los adolescentes del estudio presentaron gingivitis leve con una higiene bucal deficiente (AU).

Introduction: during many time it was believed that periodontal disease was adulthood affection, but lack of motivation in the practice of oral hygiene in the adolescence induces its beginning. Aim: to identify the periodontal status in teenagers from the Urban Secondary School “Raul Pujols”, in the city of Santiago de Cuba, in the period September 2014-March 2015. Materials and Methods: A cross-sectional, descriptive, observational study was carried out. The universe was formed by 75 both-sexes teenagers, aged 11-14 years. Russell’s periodontal index, up-dated by the Word Health Organization, and Love’s index were used. A form of data collection for the results of the physical examination was elaborated, and percentage was used as a summarizing measure. Results: mild gingivitis prevailed in 66.7 % of the teenagers, related with the deficient oral health. Female sex prevailed and the most commonly found risk factors were dental crowding and deleterious habits. Conclusions: most of the teenagers participating in the study had mild gingivitis and deficient oral health (AU).

Comparison of independent and dependent culture methods for the detection of transient bacteremia in diabetic subjects with chronic periodontitis / Comparación entre métodos de cultivo independientes y dependientes para la detección de bacteriemia transitoria en individuos diabéticos con periodontitis crónica

Introduction: Oral-derived bacteremia may occur after several dental procedures and routine daily activities. Some conditions of the oral cavity may favor episodes of bacteremia. This would be the case of patients with diabetes mellitus and periodontitis, who exhibit exacerbated gingival inflammation and may be more prone to developing oral-derived bacteremia. Objective: To compare the effectiveness of an independent culture method (quantitative real-time PCR- qCR) and the most commonly used method (BacT-ALERT 3D ® ) for the diagnosis of bacteremia. Materials and methods: Blood samples were drawn from subjects with type 2 diabetes mellitus and chronic periodontitis before and after apple chewing. Samples were processed by an automated blood culture system (BacT-ALERT 3D ® ) monitored for 15 days with suitable subculture of positive cultures. In parallel, whole DNA from blood samples was purified using a commercial kit and screened by qPCR using a universal primer set of 16S rDNA for bacteria detection. Results: Blood cultures taken before apple chewing were shown to be negative by the two diagnostic methods. After chewing, two samples (11%) showed bacterial growth by BacT-ALERT 3D ® whereas qPCR did not detect the presence of bacteria in any sample. Conclusions: qPCR did not show greater effectiveness than the BacT-ALERT 3D ® in the detection of bacteremia of oral origin.

Introducción. Las bacteriemias de origen oral pueden ocurrir después de procedimientos odontológicos y de otros actos cotidianos. Algunas condiciones de la cavidad oral favorecen las bacteriemias como en el caso de pacientes con diabetes mellitus y periodontitis que presentan inflamación gingival exacerbada. Objetivo. Comparar la eficacia de un método independiente de cultivo (PCR cuantitativa) y otro dependiente (BacT-ALERT 3D ® ) en la detección de la bacteriemia. Materiales y métodos. Se tomaron muestras de sangre de individuos con diabetes mellitus de tipo II y periodontitis, antes y después de la masticación de manzana. Una alícuota se procesó por el sistema automatizado de hemocultivo (BacT-ALERT 3D ® ) y se monitorizó durante 15 días; la otra alícuota fue tratada para la extracción del ADN y procesada por RT-PCR usando un conjunto de cebadores de 16S rDNA exclusivos para bacterias. Resultados. En las muestras tomadas antes de masticar se confirmó la ausencia de bacterias mediante los dos métodos. En las muestras tomadas después de masticar la presencia de bacterias se evidenció únicamente en dos hemocultivos y en ninguna de las muestras se detectó la presencia de bacterias con el método de RT-PCR. Conclusiones. La PCR cuantitativa no mostró mayor eficacia que el BacT-ALERT 3D ® en la detección de la bacteriemia de origen oral.

Condição bucal de pacientes cardiopatas internados no Hospital Santa Catarina de Blumenau / Buccal condition of cardiopatic patients admitted at Santa Catarina Hospital in Blumenau

Atualmente, têm-se enfatizado a relação das doenças bucais com as sistêmicas, principalmente as cardiopatias. A higiene bucal dos pacientes internados também é essencial para evitar a proliferação de bactérias e fungos, que, além de prejudicar a saúde bucal e o bem-estar do paciente, pode propiciar outras infecções e doenças sistêmicas. Objetivo: O objetivo desta pesquisa foi analisar a condição bucal de pacientes cardiopatias internados no Hospital Santa Catarina, de Blumenau/SC, no período de abril de 2011 a janeiro de 2012. Métodos: A condição clínica foi avaliada mediante os seguintes indicadores: presença ou ausência de cálculo e placa visível clinicamente, situação de edentulismo (parcial ou total), presença de sinais clínicos visíveis de inflamação da mucosa gengival, presença de cárie dental e próteses fixas ou removíveis. Resultados: Foram avaliados 150 pacientes, cujas idades variaram entre 21 e 85 anos, sendo 52% do gênero masculino e, destes, 56% apresentaram a cardiopatia fluter atrial. Entre os pacientes, 98% apresentaram algum tipo de edentulismo, parcial ou total. Apenas 2% dos pacientes informaram que realizavam higienização oral três vezes ao dia, sendo observada inflamação gengival em 47,3%, presença de cálculo em 90% e placa visível em 96,66% dos pacientes. Quanto ao uso de próteses, 98% faziam uso de algum tipo: Conclusão: Concluiu-se que a condição de saúde bucal dos pacientes avaliados pode ser considerada alarmante, Com isso, constata-se como é importante a presença de uma equipe de profissionais da odontologia no ambiente hospitalar.

Currently it has been emphasized the link between oral and systemic disease, mainly the heart disease. The oral care of hospitalized patients is also essential to avoid the proliferation of bactéria and fungi, which, in addition to affecting the oral health and well-being of the patient, may provide other infections and systemic diseases. Objective: The purpose of this research was to analyze the buccal condition of cardiac patients at Santa Catarina Hospital of Blumenau - Santa Catarina. Methods: The clinical condition was evaluated using the following indicators: dental plaque and calculus clinically visible, edentulism sistuation (partial or complete), clinical inflammation signs of the gingival mucosa, presence of dental caries and removable and fixed dental prosthesis. Results: 150 patients between 21 and 85 years-old were ealuated, 52% were male and 56% of those had the atrial flutter heart disease. Among the patients, 98% had some kind of partial or complete edentulism. Only 2% of the patients informed that oral hygiene was performed three times a day, gingival inflammation was detected in 47.3%, calculus were detected in 90% and visible plaque in 96.66% of the patients. Regarding the use of dental prothesis, 98% were using some type. It may be concluded that theses patients have na oral health conditions which is very concerning. Conclusion: According to these results it is clear how importante the presence of a dental professional team is in the hospital.

Relación de la gingivitis crónica con algunas afecciones del sistema osteomioarticular según holograma del microsistema de dientes alemán / Relationship of chronic gingivitis with some conditions of the osteomyoarticular system according to hologram of the German dental microsystem

Se realizó un estudio descriptivo y transversal de 77 pacientes de ambos sexos y edades entre 20-45 años con alguna afección del sistema osteomioarticular, atendidos en la consulta estomatológica de la parroquia Leoncio Martínez de Caracas, Venezuela, desde enero hasta Junio de 2009, a fin de relacionar la gingivitis crónica con algunas afecciones de este sistema según holograma del microsistema de dientes alemán. En la casuística, el meridiano más afectado fue pulmón-intestino grueso; predominaron las dolencias del sistema osteomioarticular en el lado izquierdo y la mayoría de campos de interferencia con la gingivitis crónica estuvieron en la parte derecha de la cavidad bucal. Asimismo, se hallaron alteraciones en la columna vertebral de los afectados con gingivitis leve, moderada y avanzada

A descriptive and cross-sectional study was conducted in 77 patients of both sexes and ages between 20-45 years with some condition of the osteomyoarticular system, attended in the dental department of the parish Leoncio Martínez from Caracas, Venezuela, from January to June 2009, in order to relate chronic gingivitis to some conditions of this system according to hologram of the German dental microsystem. In the case material the most affected meridian was lung-large intestine; osteomyoarticular system conditions prevailed on the left and most of the interference fields with chronic gingivitis were on the right side of the oral cavity. Also, abnormalities in the spine of those patients with mild, moderate and severe gingivitis were found

Efecto del tratamiento periodontal sobre la microbiota subgingival en pacientes con preeclampsia / Effect of periodontal therapy on the subgingival microbiota in preeclamptic patients

Introducción. Pocos estudios han descrito la microbiota subgingival en mujeres embarazadas con preeclampsia leve. Objetivo. Identificar cambios periodontales y de la microbiota subgingival en mujeres embarazadas con preeclampsia, después del tratamiento periodontal. Materiales y métodos. En un análisis secundario de un ensayo clínico de asignación aleatoria, se estudiaron 57 pacientes con preeclampsia en el Hospital Universitario del Valle de Cali. Se asignaron al azar 31 al grupo de intervención periodontal (detartraje y alisado subgingival ultrasónico y manual) durante su embarazo y otras 26 al grupo control (profilaxis supragingival). Se determinaron los parámetros clínicos periodontales y la microbiota subgingival a la inclusión al estudio y en el posparto. Se evaluaron 8 bacterias periodontopáticas y 2 virus herpes por reacción en cadena de la polimerasa. Se usaron las pruebas de ji al cuadrado, test de McNemar o t de Student, con un nivel de significancia de p≤ Resultados. Los grupos fueron comparables en las variables clínicas y microbiológicas al inicio del estudio. El tratamiento periodontal redujo el promedio de la profundidad de bolsa en el grupo de intervención de 2,44±0,31 a 2,31±0,24 mm (p=0,000) y en el grupo control de 2,58±0,37 a 2,44±0,39 mm (p=0,000),y el índice de sangrado, de 16,4±1,5 a 7,9±0,7 % en el primero (p=0,000), y de 17,1±1,8 a 10±0,9 %, en el segundo (p=0,002). La frecuencia de detección de microorganismos no varió de manera significativa entre los grupos. Conclusión. El raspaje y alisado radicular, así como la profilaxis supragingival, redujeron de manera significativa la profundidad a la sonda y el índice de sangrado gingival. El tratamiento periodontal no fue más efectivo que la profilaxis para reducir los organismos periodontopáticos o los virus herpes.

Introduction. Few studies have described subgingival microbiota in pregnant women with mild preeclampsia. Objective. Clinical periodontal and subgingival microbiota changes were identified in pregnant women with mild preeclampsia after periodontal treatment. Materials and methods. In a secondary analysis of a randomized clinical trial, 57 preeclamptic women were studied at Hospital Universitario del Valle in Cali, Colombia. Thirty one women were randomized to the periodontal intervention group (subgingival scaling and planing ultrasonic and manual) during pregnancy and 26 to the control group (supragingival prophylaxis). Periodontal clinical parameters and subgingival microbiota were characterized at the time of acceptance into the study and again at postpartum. Eight periodontopathic bacteria and 2 herpesviruses were assessed by polymerase chain reaction. Chi-square, McNemar or Student´s t tests were used, with a significance level of p≤0.05. Results. Both groups were comparable in the clinical and microbiological variables at baseline. Periodontal treatment reduced the average pocket depth in the intervention group from 2.4±0.3 to 2.3±0.2 mm (p<0.001) and in control group 2.6±0.4 to 2.44±0.4 mm, (p<0.001) and bleeding index 16.4±1.5% to 7.9±0.7% in the intervention group(p<0.001) and 17.1±1.8% to 10±0.9% in the control group (p=0.002). The frequency of detection of microorganisms did not differ significantly between groups. Conclusion. Scaling/root planning and supragingival prophylaxis significantly reduced the probing depth and gingival bleeding index. Periodontal treatment was not more effective than prophylaxis in reducing periodontopathic organisms or herpesvirus.

Awareness of association between periodontitis and PLBW among selected population of practising gynecologists in Andhra Pradesh.

Context: Preterm low-birth-weight (PLBW) infants are at a higher risk for a number of acute and chronic disorders. Studies point to an association between periodontal infection and increased rates of preterm birth, and pregnant mothers with periodontal diseases are at increased risk of subsequent preterm birth or low birth weight. However, the awareness level of gynecologists about this relationship is unknown. Aims: The aim of the present survey was to assess the awareness about the effects of periodontal disease on pregnancy among practicing gynecologists, and also compare such awareness between gynecologists in two places-Khammam (a district headquarter) and Hyderabad (a state capital). Settings and Design: Random, cross-sectional study in a population of practicing gynecologists from Andhra Pradesh. Materials and Methods: A random study population was selected from the practicing gynecologists in Khammam and Hyderabad. Sixty practicing gynecologists, 30 each in Khammam and Hyderabad, were approached and they consented to join the study. Data were collected in questionnaire format from the subject population. Collected data were statistically analyzed. Chi-square test with Yates correction was used to analyze the data. A " P" value of <0.05 was taken as a significant difference. Results: 73.3% of the gynecologists said that their patients complain of bleeding gums, swellings and mobility. 58.3% of the gynecologists were aware that gum diseases occur at a higher rate in pregnant females. 38.3% of the gynecologists were aware that periodontal diseases can affect the outcome of delivery. No significant difference was found between the awareness levels of gynecologists in Khammam and in Hyderabad. Conclusions: There is a need for interdisciplinary approach for the prevention of PLBW cases by the integration of periodontal care into obstetric management. Effort should be made to increase awareness among the gynecologists.

Relationship between overweight-obesity and periodontal disease in Mexico

The aim of this study was to examine the association between overweight-obesity and periodontal disease in subjects who attended the clinic of Periodontics, Faculty of Dentistry, San Luis de Potosi, Mexico. This was cross-sectional study involving 88 subjects - 60 without overweight-obesity and 28 with overweight-obesity. The following clinical parameters were evaluated: dental bacterial plaque, index of calculus, gingivitis, probing depth and periodontal disease index (PDI). When comparing the group of subjects with overweight-obesity to the control, there were statistically significant differences in the variables calculus (p=0.0015), gingivitis (p=0.0050) and periodontal disease (p=0.0154). Regarding the logistic regression analysis, the dependent variable was subjects with and without overweight-obesity and the independent variables were sex, age and periodontal disease. We found statistically significant differences (p=0.0162) with OR=3.16 in periodontal disease. Periodontal disease showed statistically significant differences in the group of subjects with overweight-obesity. The oral health of subjects with overweight- obesity should be supervised and checked in order to prevent oral alterations.

El objetivo fue asociar el sobrepeso-obesidad con la enfermedad periodontal en sujetos que asistieron a la clinica de Periodoncia de la Facultad de Estomatologia de la Universidad Autonoma de San Luis Potosi (UASLP) Mexico. Se realizo un estudio transversal con un total de 88 sujetos, 60 con sobrepeso-obesidad y 28 sin sobrepeso-obesidad. Los siguientes parametros clinicos fueron evaluados en el estudio: placa dentobacteriana, indice de calculo, profundidad de bolsa y enfermedad periodontal (PDI). Al comparar el grupo de sujetos con sobrepeso-obesidad con el control se encontraron diferencias estadisticamente significativas en las variables calculo (p=0.0015), gingivitis (p=0.0050) y enfermedad periodontal (p=0.0154). En relacion con el analisis de regresion logistica, la variable dependiente fue sujetos sin y con sobrepeso-obesidad y las independientes fueron: sexo, edad y enfermedad periodontal. Encontramos diferencias estadisticamente significativa (p=0.0162) con un OR=3.16 en enfermedad periodontal. La enfermedad periodontal mostro diferencias al comparar el grupo de sujetos con sobrepeso-obesidad con el control. Es necesario la prevencion, supervision y revision del estado de salud bucal de los pacientes con sobrepeso y obesidad para prevenir alteraciones bucales.

Principales factores de riesgo de la gingivitis crónica en pacientes de 15 a 34 años / Main risk factors of chronic gingivitis in patient of 15 to 34 years old

Se realizó un estudio de casos y controles en el consultorio estomatológico Adaca, perteneciente al Área de Salud Integral Comunitaria El Socorro, municipio de Valencia en el estado Carabobo de la República Bolivariana de Venezuela para precisar los principales factores de riesgo de la gingivitis crónica en el segundo semestre del 2007. Se escogieron los 225 pacientes de 15 a 34 años de edad, de los dos sexos, que acudieron a la consulta en ese período y reunían los criterios de inclusión. El grupo de estudio estuvo conformado por los 75 integrantes con gingivitis crónica y el grupo control por el doble de ese número, pero de personas sanas. Se utilizó el porcentaje como medida de resumen y se determinaron el riesgo relativo y el intervalo de confianza al 95 %. Hubo una correlación directamente proporcional entre los factores de riesgo analizados y la gingivitis crónica, además de que fueron significativos los indicadores de empaquetamiento de alimentos y la presencia de diabetes mellitus.

A case-control study was carried out in Adaca stomatological clinic, belonging to The Socorro Comprehensive Community Health Area, Valencia municipality in Carabobo state in the Bolivarian Republic of Venezuela to specify the main risk factors of the chronic gingivitis in the second semester of 2007. The 225 patients were chosen between 15 to 34 years old, from both sexes who attended the consulting room in that period and they fulfil the inclusion criteria. The study group was formed by 75 patients with chronic gingivitis and the control group by the double of the first group, but of healthy people. The percentage was used as the summary measure and the relative risk and the 95% confidence interval were determined. There was a directly proportional correlation between the analyzed risk factors and the chronic gingivitis, besides, the indicators of food accumulation and the presence of diabetes mellitus were significant.

The effect of smoking on gingival crevicular fluid volume during the treatment of gingivitis / Efeito do tabagismo sobre o volume de fluido crevicular gingival durante o tratamento da gengivite

Smoking is detrimental to periodontal tissues, and periodontal destruction is greater among smokers. Paradoxically, smokers seem to have less gingival bleeding than never-smokers with comparable supragingival plaque. There is scarce information about the impactof smoking on gingival crevicular fluid (GCF) volume. This singlearm study clinical trial assessed the effect of smoking on GCF volume during the treatment of gingivitis. The sample included 24 never-smokers (47.3 ± 6.7 years old, 41.7% males) and 21 smokers (45.8 ± 5.1 years old; 55% males; 19.6 ± 11.8 cigarettes/day; 24.1 ± 8.7 years of smoking) with gingivitis and chronic periodontitis. After baselinesupragingival scaling, patients received oral hygiene instructions weekly for 180 days. Participants were examined at baseline, 30, 90 and 180 days, and gingival bleeding index (GBI), bleeding on probing (BOP), periodontal probing depth (PPD) and GCF volume wererecorded. Statistical analysis was performed using linear models (Wald test, p<0.05%). Smokers had significantly smaller GCF volumes than never-smokers. This finding was not attributed to GBI, BOP or PPD. Higher volumes of GCF were significantly associated with deeper pockets. GCF was significantly reduced throughout thestudy for both smokers and never-smokers, and the largest reductionswere seen at 30 days. Smoking affected the GCF crevicular fluid volumeindependently of the presence of gingival bleeding, BOP and PPD. Smoking status and PPD should be taken into account when GCG volume and components are under investigation.

O tabagismo é capaz de alterar a resposta periodontal determinando maior expressão de destruição periodontal em pacientes fumantes. Paradoxalmente, estes pacientes apresentam menos sangramento gengival frente a uma quantidade semelhante de biofilme dental, quando comparados a pacientes que nuncafumaram. Por outro lado, existe pouca informação sobre o impacto do tabagismo sobre o volume de fluido crevicular gengival (FCG). O presente ensaio clínico de braço único teve comoobjetivo avaliar o efeito do tabagismo sobre o volume de FCG durante o tratamento da gengivite. A amostra foi composta por 24 pacientes que nunca fumaram (47.3 ± 6.7 anos, 41.7% homens) e 21 fumantes (45.8 ± 5.1 anos; 55% homens; 19.6 ± 11.8cigarros por dia; 24.1 ± 8.7 anos de exposição ao tabaco), com diagnóstico de gengivite e periodontite crônica. Os exames periodontais: Índice de Placa Visível (IPV), Índice de SangramentoGengival (ISG), Sangramento à Sondagem (SS) e Profundidade de Sondagem (PS) e a coleta de FCG foram realizados nos dias 0, 30, 90 e 180. Após a raspagem supragengival realizada no dia zero (dia 0), os pacientes receberam instrução de higienebucal semanalmente, até o dia 180. A análise estatística utilizou modelos lineares (Teste de Wald, p<0.05%). Os fumantes apresentaram um volume significativamente menor de FCG. Esteresultado não esteve associado ao ISG, SS ou PS. Sítios com maiores valores de PS apresentaram maior volume de FCG.Durante o tratamento, uma redução significante do volume de FCG foi observada em fumantes e pacientes que nunca fumaram. Conclui-se que o tabagismo influenciou o volume de FCG independente da presença de sinais inflamatórios clínicos e que o hábito de tabagismo e a PS devem ser observados quando o volume de FCG e seus componentes estiverem sob investigação.

Factores relacionados con gingivitis en niños de dos instituciones educativas de Cali / Factors related with gingivitis in children of two educational institutions from Cali

Objetivo: La caries dental y la gingivitisson enfermedades que permiten determinar las condiciones de salud bucal de una población, las cuales pudieran estar influenciadas en su desarrollo inicial, entre otros elementos, por las actitudes, creencias y el nivel educativo de los individuos. El propósito de este estudio fue conocer los factores relacionados con la aparición de gingivitis en niños entre 11 y 13 años enuna institución educativa pública y otraprivada de la ciudad de Cali. Materiales y métodos: Se realizó un estudio descriptivo de corte transversal en 69 niños de 11 a 13 años de edad, fueron incluidos todos aquellos niños de sexo masculino con gingivitis en cualquier estadío (índice de Silness and Löe) Se realizó análisis estadístico para identificar factores relacionados. Resultados: Se tomaron datos de los sujetos de ambas instituciones educativas, se encontró un grado dos de gingivitis entre los niños de la institución educativa pública (56.7%) y un grado 1 de gingivitis entre los ninos provenientes de la institución privada (64.1%). Se encontraron asociacionesentre el grado de gingivitis y el tipo de institucion, el acceso de los niños a las campañas de salud y el nivel de salario de los padres. Conclusiones: A pesar de las campañas masivas de información acerca de los hábitos saludables orales, aún se encuentran vacíos en el conocimiento de los niños sobre salud oral, los factores directamenterelacionados como la exposición a lascampañas de salud y el nivel salarial delos padres pueden tener mayor peso con el desarrollo de gingivitis.

Objective: Dental caries and gingivitis are diseases that measures the Oral Health status in a given population. Oral Health is also influenced by attitudes, beliefs and educational level of the individuals. The purpose of this study was to identify the risk factors associated gingivitis in children between 11 and 13 years coming from one public school and other private school in Cali. Materials and methods: A descriptivecross sectional study was performed using 69 male children with gingivitis (index of Silness and Löe). A statistical analysis to identify related social and higyene factors associated with gingivitis was performed. Results: Data were taken from children of both type of educative institutions. An index 2 of gingivitis was frequent in children from public school (56.7%) while a gingivitis index 1 was more prevalent in childrenfrom the private institution (64.1%). Astatistic relationship was determined forthe severity of gingivitis, the access of the children to the health Oral campaigns and the parents wage rate.Conclusions: In spite of the massivecampaigns of information about the oralhealth habits, these study determined lack of knowledge in Oral health issues among children. Variables like exposure to health campaigns, coming form Public School and wage of parents resulted associated with gingivitis.

Mecanismos patogênicos da doença periodontal associada ao diabetes melito / Pathogenic aspects of the periodontal disease associated to diabetes mellitus

OBJETIVO: Revisão sistemática do conhecimento atual sobre a associação entre diabetes melito (DM) e doença periodontal (DP) com ênfase na sua fisiopatogenia. FONTE DE DADOS: Pesquisa bibliográfica, nos últimos cinco anos, através dos bancos de dados MEDLINE e LILACS, usando as palavras-chaves "diabetes mellitus", "periodontal disease" e "periodontitis". SÍNTESE DOS DADOS: Os tecidos periodontais são as estruturas bucais mais afetadas pelo DM. O DM predispõe ao desenvolvimento da DP, a qual leva ao descontrole glicêmico, o que ressalta a importância da relação bidirecional entre essas duas doenças. Vários mecanismos estão envolvidos na fisiopatologia da DP associada ao DM: produção de produtos de glicosilação avançada, deficiente resposta imune, herança de determinados polimorfismos genéticos, alterações dos vasos sanguíneos, tecido conjuntivo e composição salivar. Na fase inicial predominam a gengivite e periodontite. Se não detectados precocemente, esses problemas podem evoluir para doença periodontal avançada. Puberdade, maior duração da doença, mau controle metabólico e higiene bucal inadequada são fatores que contribuem para progressão e agressividade da DP. CONCLUSÃO: O melhor conhecimento dos mecanismos envolvidos na fisiopatogenia da DP associada ao DM auxiliará na instituição de medidas preventivas e terapêuticas precoces. É importante que médicos e dentistas orientem os pacientes com DM sobre a necessidade de bom controle glicêmico e higiene bucal adequada para minimizar os riscos de doença periodontal.

OBJETIVE: Systematic review of present knowledge about the association between diabetes mellitus (DM) and periodontal disease (PD) with emphasis on their physiopathogenesis. DATA SOURCES: Bibliographic search through MEDLINE and LILACS databases, in the last five years, using the following descriptors: "diabetes mellitus", "periodontal disease", and "periodontitis". SUMMARY OF DATA: Periodontal tissues are the oral structures most affected by DM. DM predisposes to the development of PD, which leads to loss of glycemic control, which emphasizes the importance of the two-way relationship between these two diseases. Several mechanisms are involved in the physiopathology of PD associated with DM: production of advanced glycosilation products, deficient immune response, inheritance of certain genetic polymorphisms, alterations in blood vessels, conjunctive tissue and salivary composition. In the initial phase, gingivitis and periodontitis predominate. If not detected early, these problems can develop into advanced periodontal disease. Puberty, with its hormonal alterations, longer duration of the disease, poor metabolic control and inadequate oral hygiene are factors that contribute to PD progression and aggressiveness. CONCLUSION: Better knowledge about the mechanisms involved in the physiopathogenesis of PD associated with DM would help to institute early preventive and therapeutic measures. It is important for doctors and dentists to instruct their patients with DM about the need for good glycemic control and adequate oral hygiene, to minimize the risks for the appearance of periodontal disease and consequent loss of glycemic control.

[Comparative study of CBC, CRP and coagulation factors as the possible risk factors of cardio vascular diseases in patients with gingivitis in comparison with the control group]

Patients with periodontitis have more risk factors for cardio-vascular diseases in comparison with healthy people. Considering higher prevalence of cardio-vascular and gingival inflammatory diseases in the society, the present study was carried out to evaluate the means of CBC, CRP and coagulation factors as possible risk factors of cardio-vascular diseases in patients with gingivitis. In the case-control retrospective study, 40 male patients [2D-25 years old] referred Isfahan Dental School, who were selected by non-randomized sample method, were divided into 2 groups: group 1: gingivitis cases and group 2: controls [healthy gingiva]. The patients underwent clinical examinations and their bleeding index [CBI] was recorded. Blood sampling was carried out in the patients meeting the study criteria VII-factor were investigated. Data were analyzed statistically by t-test and ANOVA. RBC was 5.3x10[6] and 5.08x10[6] in case and control samples, WBC was 6.35x10[3] and 6.16x10[3] in case and controls and HB was 13.52 and 13.93 gr/dlit in case and control groups. Hematocryte, CRP, fibrinogen and VII factor were respectively 42.72%, 2.05, 215.3 and 176 in cases and 43.07%, 2 04, 183.5 and 181mg/dlit in controls. No significant differences were found between two groups in these factors. The results showed no significant differences between the patients having gingivitis and healthy gingival, but due to a strong probability for the bacteria and their products to enter the blood in gingivitis and aggravating atherosclerosis, it s recommended to inform the patients and society about these risk factors

Enfermedad periodontal: ¿es factor de riesgo para parto pretérmino, bajo peso al nacer o preeclampsia? / Periodontal disease: is it a risk factor for premature labor, low birth weight or preeclampsia?

OBJETIVOS: Evaluar si la enfermedad periodontal (EP) constituye un factor de riesgo de parto pretérmino, bajo peso al nacer o preeclampsia y si hay alguna relación entre las formas clínicas de la EP y los resultados obstétricos mencionados. MÉTODOS: Estudio analítico, transversal y prospectivo de todas las mujeres que tuvieron su parto en el Hospital Dr. José Penna, de la ciudad de Bahía Blanca, Argentina, entre el 1.° de febrero y el 18 de julio de 2003 y entre el 1.° de marzo y el 31 de mayo de 2004. A las mujeres que cumplieron los criterios de inclusión (ser mayor de 18 años, tener al menos 18 dientes, no ser diabética y que los hijos hubieran sobrevivido al parto) se les practicó un examen odontológico en busca de hemorragia al sondaje, movilidad dentaria o inflamación gingival y se realizaron mediciones clínicas de la pérdida de inserción. Se calcularon las razones de posibilidades (odds ratios, RP) con sus intervalos de confianza del 95 por ciento (IC95 por ciento) y se ajustaron los resultados por las variables "ser fumadora" y "tener anemia". RESULTADOS: Se registraron 2 003 nacimientos, correspondientes a 1 982 partos. Se excluyeron 420 (21,2 por ciento) mujeres por no cumplir los criterios de inclusión o por no poder realizárseles el diagnóstico odontológico previsto. De las 1 562 mujeres evaluadas, 809 (51,8 por ciento) presentaban alguna de las afecciones buscadas; de ellas, 274 (17,5 por ciento) padecían EP grave y 535 (34,3 por ciento) tenían gingivitis. En total, 149 (9,5 por ciento) partos fueron pretérmino, en 161 (10,3 por ciento) nacieron niños con bajo peso y en 157 (10,0 por ciento) se presentaron casos de preeclampsia. No se observó asociación alguna entre la EP y el parto pretérmino (RP = 1,06; IC95 por ciento: 0,74 a 1,50), el bajo peso al nacer (RP = 1,05; IC95 por ciento: 0,74 a 1,47) y la preeclampsia (RP = 0,99; IC95 por ciento: 0,70 a 1,40). El riesgo de dar a luz un niño con bajo peso al nacer en el subgrupo de fumadoras de más de 10 cigarrillos diarios fue mayor en las que tenían enfermedad periodontal grave que en las mujeres cuya salud bucal era buena (RP = 3,81; IC95 por ciento: 1,46 a 10,05; P = 0,001). Se confirmó que la anemia es un factor de riesgo de bajo peso al nacer (RP = 1,74; IC95 por ciento: 1,03 a 2,94; P = 0,02). CONCLUSIONES: No se encontró ninguna asociación significativa entre la EP y el parto pretérmino, el bajo peso al nacer o la preeclampsia.

Non-specific inflammatory gingival enlargement--a case report.

An unusual case of unilateral idiopathic gingival hyperplasia in a 6 year old child is reported and its management discussed.

Desquamative gingivitis and the presence of chronic non-specific gingivitis: study of the inflammatory infiltrate / Gengivite descamativa e a presença da gengivite crônica inespecífica: estudo do infiltrado inflamátorio

O diagnóstico clínico e histopatológico de Gengivite Descamativa (GD) envolvendo Penfigóide Benigno de Mucosa (PBM) e Líquen Plano (LP) é algumas vezes muito difícil, devido à preexistência ou superposiçäo de doença periodontal. Com o objetivo de determinar como a presença de gengivite crônica inespecífica poderia modificar o infiltrado inflamatório de lesöes gengivais de LP e de PBM, nós comparamos o percentual de células T, céculas B, macrófagos, plasmócitos, neutrófilos e células de Langerhans, utilizando a técnica imuno-histoquímica da estreptoavidina-biotina; de mastócitos, coroados pelo azul de toluidina; e de eosinófilos, através da coloraçäo pela técnica de rotina H. E. Foram selecionadas amostras oriundas de material fixado em formol e emblocado em parafina, sendo três provenientes da gengiva para cada uma das lesöes (LP I e LP II) e mais cinco casos de LP e cinco de PBM, estas situadas em outros sítios da mucosa bucal (LP II e PBM II) e utilizadas como controle. Após a contagem celular, foram feitas comparaçöes entre os grupos LP I e LP II, bem como entre os grupos PBM I e PBM II, para cada tipo celular estudado, utilizando-se o teste t de student (amostras näo pareadas). Os resultados demonstraram que näo havia diferença entre os grupos. Por outro lado, foi observado um número aumentado de eosinófilos no PBM I (p<0.05), em relaçäo ao PBM II. Assim, nós pudemos concluir que o infiltrado inflamatório de lesöes de gengivite descamativa envolvendo LP e PBM apresenta alguma alteraçäo na freqüência de seus componentes celulares devido à superposiçäo da gengivite crônica inespecífica. Entretanto, ele mantém proporçöes, dos elementos celulares estudados, semelhantes àquelas encontradas nos sítios näo gengivais